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RIPK1

Gene

receptor interacting serine/threonine kinase 1

HGNCHGNC:10019EnsemblENSG00000137275NCBI Gene8737
Locus: gene with protein productLocation: 6p25.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRIP · RIP1 · RIP-1
View full nomenclature history (5)
Alias symbolsRIP, RIP1, RIP-1
Previous namesreceptor (TNFRSF)-interacting serine-threonine kinase 1
Alias namesreceptor-interacting protein kinase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Severe Acute Respiratory Syndrome
Immunologic Deficiency Syndromes
Genetic Diseases, Inborn
Alzheimer's Disease
Parkinson's Disease
Multiple Sclerosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RipoptosomeReceptor interacting serine/threonine kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.