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RIT1

Gene

Ras like without CAAX 1

HGNCHGNC:10023EnsemblENSG00000143622NCBI Gene6016
Locus: gene with protein productLocation: 1q22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRIT · RIBB · ROC1 · MGC125864 · MGC125865
View full nomenclature history (8)
Previous symbolsRIT
Alias symbolsRIBB, ROC1, MGC125864, MGC125865
Previous namesRic (Drosophila)-like, expressed in many tissues
Alias namesRic-like, expressed in many tissues, GTP-binding protein Roc1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Noonan syndrome
RASopathy
Genetic Diseases, Inborn
Non-immune hydrops fetalis
Heart Defects, Congenital

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RAS type GTPase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.