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ROBO3

Gene

roundabout guidance receptor 3

HGNCHGNC:13433EnsemblENSG00000154134NCBI Gene64221
Locus: gene with protein productLocation: 11q24.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHGPPS · RBIG1 · FLJ21044 · HGPS
View full nomenclature history (7)
Previous symbolsHGPPS
Alias symbolsRBIG1, FLJ21044, HGPS
Previous namesroundabout (axon guidance receptor, Drosophila) homolog 3, horizontal gaze palsy with progressive scoliosis, roundabout, axon guidance receptor, homolog 3 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Diabetes, Gestational
Retinal Diseases
Kidney transplant
Tuberous Sclerosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Fibronectin type III domain containingI-set domain containingRoundabout guidance receptor family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.