RPF1

Gene

ribosome production factor 1 homolog

HGNCHGNC:30350 EnsemblENSG00000117133 NCBI Gene80135

Locus: gene with protein productLocation: 1p22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBXDC5

View full nomenclature history (5)

Previous symbolsBXDC5

Previous namesbrix domain containing 5, ribosome production factor 1 homolog (S. cerevisiae)

Alias namesRNA processing factor 1, ribosome production factor 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Asthma

Neoplasms

Infections

Diabetes Mellitus, Type 2

Temporal arteritis

Congenital myasthenic syndromes

Coronary Artery Disease

Wilms Tumor

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Brix domain containingRibosome biogenesis factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.