RTL8C

Gene

retrotransposon Gag like 8C

HGNCHGNC:2569 EnsemblENSG00000134590 NCBI Gene8933

Locus: gene with protein productLocation: Xq26.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCXX1 · FAM127A · Mart8 · Mar8 · MAR8C · SIRH5

View full nomenclature history (11)

Previous symbolsCXX1, FAM127A

Alias symbolsMart8, Mar8, MAR8C, SIRH5

Previous namesfamily with sequence similarity 127 member A, CAAX box 1, family with sequence similarity 127, member A

Alias namesSushi-Ichi retrotransposon homolog 5, mammalian retrotransposon-derived 8C

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetic Nephropathies

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Retrotransposon Gag like family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.