RXRB

Gene

retinoid X receptor beta

HGNCHGNC:10478 EnsemblENSG00000204231 NCBI Gene6257

Locus: gene with protein productLocation: 6p21.32

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Retinoic acid receptor RXR-betaP28702

Protein · therapeutic target

Clinically validated target · 4 approved medicines against this target

Member of “Retinoid X Receptors” · 1 related family paper (context, not papers about this gene)

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRCoR-1 · RXR-beta · NR2B2 · H-2RIIBP · RXRbeta

View full nomenclature history (7)

Alias symbolsRCoR-1, RXR-beta, NR2B2, H-2RIIBP, RXRbeta

Previous namesretinoid X receptor, beta

Alias namesnuclear receptor subfamily 2 group B member 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Psoriasis

Neurodegenerative Diseases

Psoriasis vulgaris

Sarcoma, Kaposi

Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Retinoid X receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.