S100A9

Gene

S100 calcium binding protein A9

HGNCHGNC:10499 EnsemblENSG00000163220 NCBI Gene6280

Locus: gene with protein productLocation: 1q21.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Protein S100-A9P06702

Protein · therapeutic target

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Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCAGB · CFAG · S100-A9 · MRP-14 · P14 · MIF · NIF · LIAG · MRP14 · MAC387 · 60B8AG · CGLB

View full nomenclature history (17)

Previous symbolsCAGB, CFAG

Alias symbolsS100-A9, MRP-14, P14, MIF, NIF, LIAG, MRP14, MAC387, 60B8AG, CGLB

Previous namescalgranulin B, S100 calcium-binding protein A9 (calgranulin B)

Alias namesCalprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Immunologic Deficiency Syndromes

Response to antihypertensive drug

Neoplasms

Psoriasis

Carcinoma, Hepatocellular

Colorectal Neoplasms

Alzheimer's Disease

Idiopathic Pulmonary Fibrosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

S100 calcium binding proteinsEF-hand domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.