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SAR1B

Gene

secretion associated Ras related GTPase 1B

HGNCHGNC:10535EnsemblENSG00000152700NCBI Gene51128
Locus: gene with protein productLocation: 5q31.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSARA2
View full nomenclature history (5)
Previous symbolsSARA2
Previous namessecretion associated, Ras related GTPase 1B, SAR1 homolog B (S. cerevisiae), SAR1a gene homolog (S. cerevisiae) 2, SAR1a gene homolog 2 (S. cerevisiae)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Neurodegenerative Diseases
Alzheimer's Disease
Hereditary chronic pancreatitis
Colorectal Neoplasms
Pancreatic triacylglycerol lipase deficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ARF GTPase familyCoat protein complex II

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.