SCN7A

Gene

sodium voltage-gated channel alpha subunit 7

HGNCHGNC:10594 EnsemblENSG00000136546 NCBI Gene6332

Locus: gene with protein productLocation: 2q24.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Sodium channel protein type 7 subunit alphaQ01118

Protein · therapeutic target

Clinically validated target · 59 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSCN6A · Nav2.1 · Nav2.2 · NaG

View full nomenclature history (8)

Previous symbolsSCN6A

Alias symbolsNav2.1, Nav2.2, NaG

Previous namessodium channel, voltage-gated, type VII, alpha, sodium channel, voltage-gated, type VI, alpha, sodium channel, voltage-gated, type VII, alpha subunit, sodium channel, voltage gated, type VII alpha subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Epilepsy

Major depressive disorder

Migraine Disorders

Amyotrophic Lateral Sclerosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.