SCNN1B

Gene

sodium channel epithelial 1 subunit beta

HGNCHGNC:10600 EnsemblENSG00000168447 NCBI Gene6338

Locus: gene with protein productLocation: 16p12.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asENaCbeta

View full nomenclature history (4)

Alias symbolsENaCbeta

Previous namessodium channel, non voltage gated 1 beta subunit

Alias namesamiloride-sensitive sodium channel subunit beta, Liddle syndrome

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Bronchiectasis with or without elevated sweat chloride 1

Hypertension

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Sodium channels epithelial

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-01-15.

Open TargetsGene–disease associations from the Open Targets Platform.