Back to discover

SDHC

Gene

succinate dehydrogenase complex subunit C

HGNCHGNC:10682EnsemblENSG00000143252NCBI Gene6391
Locus: gene with protein productLocation: 1q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPGL3 · CYB560 · cybL
View full nomenclature history (8)
Previous symbolsPGL3
Alias symbolsCYB560, cybL
Previous namessuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kD, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
Alias namessuccinate dehydrogenase cytochrome b560 subunit, succinate dehydrgenase cytochrome b, large subunit of cytochrome b

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Gastrointestinal Stromal Tumors
Inherited cancer-predisposing syndrome
Neoplastic Syndromes, Hereditary
Neurodegenerative Diseases
Paraganglioma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mitochondrial complex II: succinate dehydrogenase subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.