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SERPINF1

Gene

serpin family F member 1

HGNCHGNC:8824EnsemblENSG00000132386NCBI Gene5176
Locus: gene with protein productLocation: 17p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPEDF · EPC-1 · PIG35
View full nomenclature history (7)
Previous symbolsPEDF
Alias symbolsEPC-1, PIG35
Previous namesserine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1, pigment epithelium-derived factor
Alias namesalpha-2 antiplasmin, proliferation-inducing protein 35

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteogenesis Imperfecta
Neurodegenerative Diseases
Alzheimer's Disease
Breast Neoplasms
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serpin peptidase inhibitors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.