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SFRP4

Gene

secreted frizzled related protein 4

HGNCHGNC:10778EnsemblENSG00000106483NCBI Gene6424
Locus: gene with protein productLocation: 7p14.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asfrpHE · FRP-4 · FRZB-2
View full nomenclature history (4)
Alias symbolsfrpHE, FRP-4, FRZB-2
Previous namessecreted frizzled-related protein 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Colorectal adenocarcinoma
Gastric carcinoma
Colonic Neoplasms
Skin squamous cell carcinoma
Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Secreted frizzled-related proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.