SHOC2

Gene

SHOC2 leucine rich repeat scaffold protein

HGNCHGNC:15454 EnsemblENSG00000108061 NCBI Gene8036

Locus: gene with protein productLocation: 10q25.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA0862 · SOC2 · SUR-8 · SOC-2 · SUR8

View full nomenclature history (9)

Alias symbolsKIAA0862, SOC2, SUR-8, SOC-2, SUR8

Previous namessoc-2 (suppressor of clear, C.elegans) homolog, soc-2 suppressor of clear homolog (C. elegans), SHOC2 leucine-rich repeat scaffold protein, SHOC2, leucine rich repeat scaffold protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Noonan syndrome

RASopathy

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.