Back to discover

SIGMAR1

Gene

sigma non-opioid intracellular receptor 1

Locus: gene with protein productLocation: 9p13.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asOPRS1 · SR-BP1
View full nomenclature history (3)
Previous symbolsOPRS1
Alias symbolsSR-BP1
Previous namesopioid receptor, sigma 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

No gene–disease associations are recorded in the graph for this gene yet. Associations appear here as they are ingested and their disease is resolved to a canonical entity.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.