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SLC12A2

Gene

solute carrier family 12 member 2

HGNCHGNC:10911EnsemblENSG00000064651NCBI Gene6558
Locus: gene with protein productLocation: 5q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNKCC1 · BSC2 · BSC-2 · PPP1R141 · CCC1
View full nomenclature history (9)
Alias symbolsNKCC1, BSC2, BSC-2, PPP1R141, CCC1
Previous namessolute carrier family 12 (sodium/potassium/chloride transporter), member 2
Alias namesbasolateral Na-K-Cl symporter, protein phosphatase 1, regulatory subunit 141, bumetanide-sensitive cotransporter type 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hearing Loss
Hypothyroidism
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunitsSolute carrier family 12

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.