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SLC25A4

Gene

solute carrier family 25 member 4

HGNCHGNC:10990EnsemblENSG00000151729NCBI Gene291
Locus: gene with protein productLocation: 4q35.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

ADP/ATP translocase 1P12235

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPEO3 · PEO2 · ANT1 · T1 · AAC1
View full nomenclature history (11)
Previous symbolsPEO3, PEO2, ANT1
Alias symbolsT1, AAC1
Previous namessolute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4, Adenine nucleotide translocator 1, progressive external ophthalmoplegia 3, progressive external ophthalmoplegia 2
Alias namesADP/ATP translocase 1, ADP/ATP carrier 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Cardiomyopathy, Hypertrophic
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Solute carrier family 25

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.