SLC5A1

Gene

solute carrier family 5 member 1

HGNCHGNC:11036 EnsemblENSG00000100170 NCBI Gene6523

Locus: gene with protein productLocation: 22q12.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Sodium/glucose cotransporter 1P13866

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSGLT1 · D22S675 · NAGT · SGLT-1

View full nomenclature history (6)

Previous symbolsSGLT1

Alias symbolsD22S675, NAGT, SGLT-1

Previous namessolute carrier family 5 (sodium/glucose cotransporter), member 1

Alias namessodium/glucose cotransporter 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 2

Heart Failure

Diabetes Mellitus, Type 1

Kidney Failure, Chronic

Diabetes Mellitus

Diabetic Nephropathies

Cardiomyopathy, Hypertrophic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Solute carrier family 5

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.