SMAD9

Gene

SMAD family member 9

HGNCHGNC:6774 EnsemblENSG00000120693 NCBI Gene4093

Locus: gene with protein productLocation: 13q13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMADH6 · MADH9 · SMAD8 · SMAD8/9

View full nomenclature history (6)

Previous symbolsMADH6, MADH9

Alias symbolsSMAD8, SMAD8/9

Previous namesMAD, mothers against decapentaplegic homolog 9 (Drosophila), SMAD, mothers against DPP homolog 9 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Pulmonary arterial hypertension

Idiopathic pulmonary arterial hypertension

Colorectal Neoplasms

Lung Neoplasms

Colonic Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SMAD family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.