SMARCB1

Gene

SWI/SNF related BAF chromatin remodeling complex subunit B1

HGNCHGNC:11103 EnsemblENSG00000099956 NCBI Gene6598

Locus: gene with protein productLocation: 22q11.23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSNF5L1 · BAF47 · Ini1 · INI-1 · Snr1 · hSNFS · Sfh1p · RDT · PPP1R144 · SNF5

View full nomenclature history (15)

Previous symbolsSNF5L1

Alias symbolsBAF47, Ini1, INI-1, Snr1, hSNFS, Sfh1p, RDT, PPP1R144, SNF5

Previous namesSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

Alias namessucrose nonfermenting, yeast, homolog-like 1, integrase interactor 1, malignant rhabdoid tumor suppressor, protein phosphatase 1, regulatory subunit 144

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Rhabdoid Tumor

Neoplastic Syndromes, Hereditary

Inherited cancer-predisposing syndrome

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase 1 regulatory subunitsBAF complex subunitsPBAF complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-09-19.

Open TargetsGene–disease associations from the Open Targets Platform.