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SMC3

Gene

structural maintenance of chromosomes 3

HGNCHGNC:2468EnsemblENSG00000108055NCBI Gene9126
Locus: gene with protein productLocation: 10q25.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCSPG6 · HCAP · BAM · SMC3L1 · bamacan
View full nomenclature history (7)
Previous symbolsCSPG6
Alias symbolsHCAP, BAM, SMC3L1, bamacan
Previous nameschondroitin sulfate proteoglycan 6 (bamacan)
Alias namesbamacan proteoglycan

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

De Lange Syndrome
Genetic Diseases, Inborn
Heart Arrest
Neurodegenerative Diseases
Heart Defects, Congenital
Autism Spectrum Disorder
Neurodevelopmental Disorders
Neuromuscular Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ProteoglycansStructural maintenance of chromosomes proteinsCohesin complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.