SOCS1

Gene

suppressor of cytokine signaling 1

HGNCHGNC:19383 EnsemblENSG00000185338 NCBI Gene8651

Locus: gene with protein productLocation: 16p13.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSOCS-1 · SSI-1 · JAB · TIP3 · Cish1

View full nomenclature history (5)

Alias symbolsSOCS-1, SSI-1, JAB, TIP3, Cish1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lymphoma, Large B-Cell, Diffuse

Psoriasis

Common variable immunodeficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SH2 domain containingSuppressors of cytokine signaling

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-01-15.

Open TargetsGene–disease associations from the Open Targets Platform.