Back to discover

SPINK5

Gene

serine peptidase inhibitor Kazal type 5

HGNCHGNC:15464EnsemblENSG00000133710NCBI Gene11005
Locus: gene with protein productLocation: 5q32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asVAKTI · LEKTI · LETKI · NETS · NS · FLJ21544 · FLJ97536 · FLJ97596 · FLJ99794 · DKFZp686K19184
View full nomenclature history (12)
Alias symbolsVAKTI, LEKTI, LETKI, NETS, NS, FLJ21544, FLJ97536, FLJ97596, FLJ99794, DKFZp686K19184
Previous namesserine protease inhibitor, Kazal type 5
Alias nameslymphoepithelial Kazal-type-related inhibitor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Erythematosquamous dermatosis
Dermatitis, Seborrheic
Neurodegenerative Diseases
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serine peptidase inhibitors, Kazal type

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.