SPOCK1

Gene

SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1

HGNCHGNC:11251 EnsemblENSG00000152377 NCBI Gene6695

Locus: gene with protein productLocation: 5q31.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTIC1 · SPOCK · testican-1

View full nomenclature history (5)

Previous symbolsTIC1, SPOCK

Alias symbolstestican-1

Previous namessparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican), SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Abnormality of serum enzyme levels

Diabetes Mellitus, Type 2

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

SPARC family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.