SPRN

Gene

shadow of prion protein

HGNCHGNC:16871 EnsemblENSG00000203772 NCBI Gene503542

Locus: gene with protein productLocation: 10q26.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asShadoo · bA108K14.1 · FLJ41197

View full nomenclature history (5)

Alias symbolsShadoo, bA108K14.1, FLJ41197

Previous namesshadow of prion protein homolog (zebrafish)

Alias nameshypothetical protein BC004409

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Obesity due to melanocortin 4 receptor deficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.