SRSF2

Gene

serine and arginine rich splicing factor 2

HGNCHGNC:10783 EnsemblENSG00000161547 NCBI Gene6427

Locus: gene with protein productLocation: 17q25.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSFRS2 · SFRS2A · SC-35 · SC35 · PR264

View full nomenclature history (8)

Previous symbolsSFRS2

Alias symbolsSFRS2A, SC-35, SC35, PR264

Previous namessplicing factor, arginine/serine-rich 2, serine/arginine-rich splicing factor 2

Alias namesSR splicing factor 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Myeloid, Acute

Myelodysplastic syndrome

Hemorrhagic disease

Chronic myelomonocytic leukemia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RNA binding motif containingSerine and arginine rich splicing factorsMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.