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TBX3

Gene

T-box transcription factor 3

HGNCHGNC:11602EnsemblENSG00000135111NCBI Gene6926
Locus: gene with protein productLocation: 12q24.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asUMS · TBX3-ISO · XHL
View full nomenclature history (5)
Previous symbolsUMS
Alias symbolsTBX3-ISO, XHL
Previous namesulnar mammary syndrome, T-box 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Breast adenocarcinoma
Genetic Diseases, Inborn
Atrial Fibrillation
Prostate carcinoma
Colorectal adenocarcinoma
Colonic Polyps
Hypertension

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

T-box transcription factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.