TGM3

Gene

transglutaminase 3

HGNCHGNC:11779 EnsemblENSG00000125780 NCBI Gene7053

Locus: gene with protein productLocation: 20p13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTGE

View full nomenclature history (3)

Alias symbolsTGE

Previous namestransglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)

Alias namesE polypeptide, protein-glutamine-gamma-glutamyltransferase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Basal cell carcinoma

Skin Neoplasms

Uncombable hair syndrome

Neoplasms

Cutaneous melanoma

Carcinoma, Squamous Cell

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Transglutaminases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.