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THPO

Gene

thrombopoietin

HGNCHGNC:11795EnsemblENSG00000090534NCBI Gene7066
Locus: gene with protein productLocation: 3q27.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMGDF · TPO · MPLLG
View full nomenclature history (11)
Previous symbolsMGDF
Alias symbolsTPO, MPLLG
Alias namesprepro-thrombopoietin, megakaryocyte stimulating factor, myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor, MPL ligand, megakaryocyte colony-stimulating factor, c-mpl ligand, thrombopoietin nirs

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Thrombocytopenia 4
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Receptor ligands

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.