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TNFRSF10B

Gene

TNF receptor superfamily member 10b

HGNCHGNC:11905EnsemblENSG00000120889NCBI Gene8795
Locus: gene with protein productLocation: 8p21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDR5 · KILLER · TRICK2A · TRAIL-R2 · TRICKB · CD262 · TRAILR2
View full nomenclature history (8)
Alias symbolsDR5, KILLER, TRICK2A, TRAIL-R2, TRICKB, CD262, TRAILR2
Previous namestumor necrosis factor receptor superfamily, member 10b

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Basal cell carcinoma
Squamous Cell Carcinoma of Head and Neck
Carcinoma, Renal Cell
Intestinal Diseases
Vascular Diseases
Prostate carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesTumor necrosis factor receptor superfamily

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.