TNNI3

Gene

troponin I3, cardiac type

HGNCHGNC:11947 EnsemblENSG00000129991 NCBI Gene7137

Locus: gene with protein productLocation: 19q13.42

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCMD2A · TNNC1 · CMH7 · cTNI

View full nomenclature history (7)

Previous symbolsCMD2A

Alias symbolsTNNC1, CMH7, cTNI

Previous namescardiomyopathy, dilated 2A (autosomal recessive), troponin I type 3 (cardiac), troponin I type 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cardiomyopathy, Hypertrophic

Familial isolated dilated cardiomyopathy

Rare familial disorder with hypertrophic cardiomyopathy

Cardiomyopathies

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Troponin complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.