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TPM1

Gene

tropomyosin 1

HGNCHGNC:12010EnsemblENSG00000140416NCBI Gene7168
Locus: gene with protein productLocation: 15q22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC15orf13 · CMH3
View full nomenclature history (5)
Previous symbolsC15orf13, CMH3
Previous nameschromosome 15 open reading frame 13, cardiomyopathy, hypertrophic 3, tropomyosin 1 (alpha)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cardiomyopathy, Hypertrophic
Left ventricular noncompaction
Familial isolated dilated cardiomyopathy
Rare familial disorder with hypertrophic cardiomyopathy
Cardiomyopathies
Cardiomyopathy, Dilated
Familial hypertrophic cardiomyopathy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tropomyosins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.