TREML1

Gene

triggering receptor expressed on myeloid cells like 1

HGNCHGNC:20434 EnsemblENSG00000161911 NCBI Gene340205

Locus: gene with protein productLocation: 6p21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTLT1 · dJ238O23.3

View full nomenclature history (4)

Alias symbolsTLT1, dJ238O23.3

Previous namestriggering receptor expressed on myeloid cells-like 1

Alias namesTREM-like transcript 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Parkinson's Disease

Alzheimer's Disease

Rare hemorrhagic disorder due to a constitutional platelet anomaly

Autosomal dominant macrothrombocytopenia

Von Willebrand disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

V-set domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.