TRIB1

Gene

tribbles pseudokinase 1

HGNCHGNC:16891 EnsemblENSG00000173334 NCBI Gene10221

Locus: gene with protein productLocation: 8q24.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC8FW · GIG2 · TRB1

View full nomenclature history (4)

Alias symbolsC8FW, GIG2, TRB1

Previous namestribbles homolog 1 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Diabetes Mellitus

Coronary Artery Disease

Liver Diseases

Hyperlipidemias

Metabolic Diseases

Non-alcoholic Fatty Liver Disease

Thyroid gland carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tribbles pseudokinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.