TTLL4

Gene

tubulin tyrosine ligase like 4

HGNCHGNC:28976 EnsemblENSG00000135912 NCBI Gene9654

Locus: gene with protein productLocation: 2q35

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA0173

View full nomenclature history (2)

Alias symbolsKIAA0173

Previous namestubulin tyrosine ligase-like family member 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Carcinoma, Hepatocellular

Homozygous familial hypercholesterolemia

Breast Neoplasms

Neoplasms

Familial hypercholesterolemia

Hypercholesterolemia, autosomal dominant, 3

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tubulin tyrosine ligase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.