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UBQLN2

Gene

ubiquilin 2

HGNCHGNC:12509EnsemblENSG00000188021NCBI Gene29978
Locus: gene with protein productLocation: Xp11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asChap1 · Dsk2 · RIHFB2157 · CHAP1/DSK2 · PLIC-2 · PLIC2 · N4BP4 · LIC-2
View full nomenclature history (9)
Alias symbolsChap1, Dsk2, RIHFB2157, CHAP1/DSK2, PLIC-2, PLIC2, N4BP4, LIC-2
Alias namesNEDD4 binding protein 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Amyotrophic Lateral Sclerosis
Hypertension
Dementia, Vascular
Frontotemporal Dementia
Alzheimer's Disease
Adenocarcinoma of Lung
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ubiquilin family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-08-16.
Open TargetsGene–disease associations from the Open Targets Platform.