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UNG

Gene

uracil DNA glycosylase

HGNCHGNC:12572EnsemblENSG00000076248NCBI Gene7374
Locus: gene with protein productLocation: 12q24.11

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Uracil-DNA glycosylaseP13051

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDGU · UDG · UNG1 · UNG2 · HIGM4
View full nomenclature history (6)
Previous symbolsDGU
Alias symbolsUDG, UNG1, UNG2, HIGM4
Alias namesuracil-DNA glycosylase 1, uracil-DNA glycosylase 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Food Hypersensitivity
Neoplasms
Infections
Lymphoma
Common variable immunodeficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DNA glycosylases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.