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ZNF486

Gene

zinc finger protein 486

HGNCHGNC:20807EnsemblENSG00000256229NCBI Gene90649
Locus: gene with protein productLocation: 19p12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKRBO2 · MGC2396
View full nomenclature history (3)
Previous symbolsKRBO2
Alias symbolsMGC2396
Previous namesKRAB domain only 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alzheimer's Disease
Retinitis Pigmentosa
Cone rod dystrophy
Leber Congenital Amaurosis
Early-onset non-syndromic cataract
Congenital glaucoma
Posterior polar cataract

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typeKRAB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.