Protein / target

Angiotensin-converting enzyme 2

ACE2Q9BYF1
UniProt: Q9BYF1
31
Research papers

Protein at a glance

Research activity

Actively researched

31 papers · latest 2024

Derived from structured UniProt, Open Targets and literature data on this page.

Research activity

31 papers · to 2024

Papers linked directly to this protein. This is the protein's own literature — descriptor-derived papers are kept separate below.

Most cited

A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9.2,163 cites

Donoghue M · Circulation research · 2000

The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status.2,162 cites

Guo YR · Military Medical Research · 2020

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.1,663 cites

Zhang H · Intensive care medicine · 2020

Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues.1,092 cites

Li MY · Infectious diseases of poverty · 2020

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia.896 cites

Brann DH · Science advances · 2020

Recent

Post-SARS-CoV-2 infection and post-vaccine-related neurological complications share clinical features and the same positivity to anti-ACE2 antibodies.

Bellucci M · Frontiers in immunology · 2024

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters.

Halfmann PJ · Nature · 2022

COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation.

Aboudounya MM · Mediators of inflammation · 2021

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.

Muus C · Nature medicine · 2021

Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.

Zhang Q · Nature cell biology · 2021

Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.

Thomson EC · Cell · 2021

SARS-CoV-2 infection of the oral cavity and saliva.

Huang N · Nature medicine · 2021

The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status.

Guo YR · Military Medical Research · 2020

Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics.

Gurwitz D · Drug development research · 2020

Angiotensin-converting enzyme 2 (ACE2), SARS-CoV-2 and the pathophysiology of coronavirus disease 2019 (COVID-19).

Bourgonje AR · The Journal of pathology · 2020

Europe PMC papers linked directly to this protein.