Protein / target

C-C chemokine receptor type 2

CCR2P41597
UniProt: P41597
9
Research papers

Protein at a glance

Research activity

Emerging research

9 papers · latest 2024

Derived from structured UniProt, Open Targets and literature data on this page.

Research activity

9 papers · to 2024

Papers linked directly to this protein. This is the protein's own literature — descriptor-derived papers are kept separate below.

Most cited

CCR2 modulates inflammatory and metabolic effects of high-fat feeding.1,230 cites

Weisberg SP · The Journal of clinical investigation · 2006

Genetic mechanisms of critical illness in COVID-19.1,129 cites

Pairo-Castineira E · Nature · 2021

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques.1,070 cites

Tacke F · The Journal of clinical investigation · 2007

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.832 cites

Boring L · The Journal of clinical investigation · 1997

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.569 cites

Folkersen L · Nature metabolism · 2020

Recent

Visualizing Immune Checkpoint Inhibitors Derived Inflammation in Atherosclerosis.

Lou L · Circulation research · 2024

CCL2-CCR2 signaling axis in obesity and metabolic diseases.

Wu Y · Journal of cellular physiology · 2024

Genetic mechanisms of critical illness in COVID-19.

Pairo-Castineira E · Nature · 2021

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.

Folkersen L · Nature metabolism · 2020

CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis.

Yang H · Molecular cancer · 2020

Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.

Shi L · Nature communications · 2019

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques.

Tacke F · The Journal of clinical investigation · 2007

CCR2 modulates inflammatory and metabolic effects of high-fat feeding.

Weisberg SP · The Journal of clinical investigation · 2006

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.

Boring L · The Journal of clinical investigation · 1997

Europe PMC papers linked directly to this protein.