Protein / target

Cellular tumor antigen p53

TP53P04637
UniProt: P04637
21
Research papers

Protein at a glance

Research activity

Emerging research

21 papers · latest 2025

Derived from structured UniProt, Open Targets and literature data on this page.

Research activity

21 papers · to 2025

Papers linked directly to this protein. This is the protein's own literature — descriptor-derived papers are kept separate below.

Most cited

Cellular response to oxidative stress: signaling for suicide and survival.1,620 cites

Martindale JL · Journal of cellular physiology · 2002

Targeting p53 pathways: mechanisms, structures, and advances in therapy.673 cites

Wang H · Signal transduction and targeted therapy · 2023

PDL1 Regulation by p53 via miR-34.513 cites

Cortez MA · Journal of the National Cancer Institute · 2016

Copper metabolism in cell death and autophagy.504 cites

Xue Q · Autophagy · 2023

Targeting mutant p53 for cancer therapy: direct and indirect strategies.379 cites

Hu J · Journal of hematology & oncology · 2021

Recent

Decoding p53 tumor suppression: a crosstalk between genomic stability and epigenetic control?

Janic A · Cell death and differentiation · 2025

Targeting apoptotic pathways for cancer therapy.

Tian X · The Journal of clinical investigation · 2024

Effects of KRAS, STK11, KEAP1, and TP53 mutations on the clinical outcomes of immune checkpoint inhibitors among patients with lung adenocarcinoma.

Liang Y · PloS one · 2024

Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways.

Park JC · Nature communications · 2024

A high efficiency precision genome editing method with CRISPR in iPSCs.

Singh A · Scientific reports · 2024

Evolutionary trajectories of small cell lung cancer under therapy.

George J · Nature · 2024

Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy.

Song B · Cancer communications (London, England) · 2024

Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis.

Chaudagar K · Clinical cancer research : an official journal of the American Association for Cancer Research · 2023

Copper metabolism in cell death and autophagy.

Xue Q · Autophagy · 2023

Targeting p53 pathways: mechanisms, structures, and advances in therapy.

Wang H · Signal transduction and targeted therapy · 2023

Europe PMC papers linked directly to this protein.