Protein / target

Nuclear factor erythroid 2-related factor 2

NFE2L2Q16236
UniProt: Q16236
35
Research papers

Protein at a glance

Research activity

Actively researched

35 papers · latest 2025

Derived from structured UniProt, Open Targets and literature data on this page.

Research activity

35 papers · to 2025

Papers linked directly to this protein. This is the protein's own literature — descriptor-derived papers are kept separate below.

Most cited

Ferroptosis: molecular mechanisms and health implications.3,233 cites

Tang D · Cell research · 2021

ROS and ROS-Mediated Cellular Signaling.1,332 cites

Zhang J · Oxidative medicine and cellular longevity · 2016

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.843 cites

Linker RA · Brain : a journal of neurology · 2011

Programmed Cell-Death by Ferroptosis: Antioxidants as Mitigators.468 cites

Kajarabille N · International journal of molecular sciences · 2019

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development.443 cites

Robledinos-Antón N · Oxidative medicine and cellular longevity · 2019

Recent

Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide.

Goyal L · CNS & neurological disorders drug targets · 2025

Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases.

Rojo AI · Redox biology · 2025

The Role of P62/Nrf2/Keap1 Signaling Pathway in Lead-Induced Neurological Dysfunction.

Peng D · CNS neuroscience & therapeutics · 2025

Regulatory Dynamics of Nrf2 With Sirtuins in the Brain: Exploring Cellular Metabolism, Synaptic Plasticity, and Defense Mechanisms.

Perez Lao EJ · Journal of neurochemistry · 2025

Health position paper and redox perspectives - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases.

Cuadrado A · Redox biology · 2025

Understanding chronic inflammation: couplings between cytokines, ROS, NO, Ca<sub>i</sub> <sup>2+</sup>, HIF-1α, Nrf2 and autophagy.

Michalak KP · Frontiers in immunology · 2025

FNDC5 prevents oxidative stress and neuronal apoptosis after traumatic brain injury through SIRT3-dependent regulation of mitochondrial quality control.

Ge Y · Cell death & disease · 2024

Regulation of immunomodulatory networks by Nrf2-activation in immune cells: Redox control and therapeutic potential in inflammatory diseases.

Pant T · Redox biology · 2024

Nebulized Glutathione as a Key Antioxidant for the Treatment of Oxidative Stress in Neurodegenerative Conditions.

Lana JV · Nutrients · 2024

Genomic and Immunophenotypic Landscape of Acquired Resistance to PD-(L)1 Blockade in Non-Small-Cell Lung Cancer.

Ricciuti B · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024

Europe PMC papers linked directly to this protein.