Disease

Adrenal Cortex Neoplasms

Active therapeutic pipelineEmerging research

MeSHAdrenal Cortex Neoplasms

Publications

Clinical trials

2020

Latest publication

Latest activity

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Recent clinical, regulatory, research and industry developments relating to this disease.

Adrenocortical carcinomas and malignant phaeochromocytomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Research2020-08-27Annals of oncology : official journal of the European Society for Medical Oncology

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low

Key developments

1 clinical trial expected to report results, the earliest in Q4 2027.

Upcoming Milestones

Q4 2027Phase II Study Evaluating the Efficacy of PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Major developments

Upcoming trial readoutHigh impact

Phase II Study Evaluating the Efficacy of PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Results expected Q4 20272026-07-10

Clinical Milestones1View

Results expected 1

2026-07-10Phase II Study Evaluating the Efficacy of PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical CarcinomaResults expected Q4 2027

Activity timeline1

2026-07-10ClinicalPhase II Study Evaluating the Efficacy of PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical CarcinomaResults expected Q4 2027

Clinical trials

1 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme

All trials

Active

Late-stage

Completed

Recruiting

Phase 2 · Recruiting · National Cancer Institute (NCI)

Recently completed

Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-Pathway in Metastatic, Recurrent or Primary Unresectable Adrenocortical Cancer

Phase 2 · Completed · National Cancer Institute (NCI)

A Study of Combination Chemotherapy & Surgical Resection in the Tx of Adrenocortical Cancer: Mitotane & Continuous Infusion Doxorubicin, Vincristine & Etoposide w/the P-glycoprotein Antagonist, Tariquidar (XR9576), Before & After Surgical Resection

Phase 2 · Completed · National Cancer Institute (NCI)

Research activity

1 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Most influential

Adrenocortical carcinomas and malignant phaeochromocytomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Annals of oncology : official journal of the European Society for Medical Oncology · 2020 · 276 cites

Recent publications

Adrenocortical carcinomas and malignant phaeochromocytomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Annals of oncology : official journal of the European Society for Medical Oncology · 2020 · 276 cites

Major themes4

Adrenal Cortex Neoplasms1
Adrenal Gland Neoplasms1
Adrenocortical Carcinoma1
Pheochromocytoma1

Leading journals1

Annals of oncology : official journal of the European Society for Medical Oncology1

Leading researchers8

Assie G1
Baudin E1
Berruti A1
de Krijger R1
de la Fouchardiere C1
Eisenhofer G1
Fassnacht M1
Haak HR1

Affiliations (unnormalised)6

Centre Léon Bérard1
Department of Clinical and Biological Sciences1
Department of Medicine III and Institute of Clinical Chemistry and Laboratory Medicine1
Maastricht University Medical Centre1
Reference Centre for Rare Adrenal Diseases1
San Luigi Hospital - Orbassano1

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Tumors or cancers of the ADRENAL CORTEX.

Identifiers

MeSHAdrenal Cortex Neoplasms

References & data sources

Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
Related entities are derived from literature co-mention (studied together) — associative, not causal.