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CYP11B1

Gene

cytochrome P450 family 11 subfamily B member 1

HGNCHGNC:2591EnsemblENSG00000160882NCBI Gene1584
Locus: gene with protein productLocation: 8q24.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Cytochrome P450 11B1, mitochondrialP15538

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCYP11B · P450C11 · FHI · CPN1
View full nomenclature history (7)
Previous symbolsCYP11B
Alias symbolsP450C11, FHI, CPN1
Previous namescytochrome P450, family 11, subfamily B, polypeptide 1, cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1
Alias namessteroid 11-beta-monooxygenase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Adrenal Hyperplasia, Congenital
Cushing's Syndrome
Adrenal gland disorder
Neoplasms
Adrenal Cortex Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Cytochrome P450 family 11

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.