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Disease

Alcohol drinking

Late-stage therapeutic development

Also known as alcohol consumption.

19
Clinical trials
12
Associated genes
6
Related proteins
Current focus
Mucin-16 biologySerotransferrin biologyTherapeutic developmentMetabolic & lifestyle factors
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

Evaluating How Alcohol Impacts Physiological Responses and Perception During Heat Exposure

Clinical trial2026-09-24Status changed to Completed · ClinicalTrials.gov

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 2 clinical trials expected to report results, the earliest in Q4 2026.
  • 3 industry developments reported.
Upcoming Milestones
Major developments
Major trial resultsImportant
Marijuana's Impact on Alcohol Motivation and Consumption
Results posted2026-04-21
Upcoming trial readoutImportant
Nicotinic Receptor Genetic Variation and Alcohol Reward
Results expected Q4 20262026-08-18
Clinical Milestones4View
Results posted 1
Results expected 2
Recently completed 1
Industry & Market3View
Activity timeline7

Clinical trials

13 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Clinical programme
19
All trials
6
Active
6
Late-stage
6
Completed
Late-stage studies

Effects of Ketone Ester on Brain Function and Alcohol Consumption in Alcohol Use Disorder

Phase 2/3 · Recruiting · University of Pennsylvania

Effect of Nutritional Ketosis on Alcohol Metabolism

Phase 2/3 · Active, not recruiting · University of Pennsylvania

Efficacy of Gabapentin in Alcohol Dependency Treatment: a Double-blinded Randomized Placebo-controlled Trial

Phase 3 · Completed · Chulalongkorn University

Topiramate Treatment of Problem Drinkers

Phase 4 · Completed · UConn Health

Research on Translational Outcomes of Alcohol (Project RETRO)

Phase 4 · Withdrawn · University of Washington

Determining the Combined Effects of THC and Alcohol on Driving Performance

Phase 4 · Withdrawn · Lakehead University
Recruiting

Effects of Ketone Ester on Brain Function and Alcohol Consumption in Alcohol Use Disorder

Phase 2/3 · Recruiting · University of Pennsylvania

Cannabis' Impact on Alcohol Consumption: Integrating Laboratory and Ecological Momentary Assessment Methods

Phase 2 · Recruiting · Brown University

Nicotinic Receptor Genetic Variation and Alcohol Reward

Phase 1 · Recruiting · National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design

N/A · Recruiting · University of Illinois at Urbana-Champaign
Recently completed

Neuroscience-Informed Treatment Development for Adolescent Alcohol Use

Phase 2 · Completed · Medical University of South Carolina

Marijuana's Impact on Alcohol Motivation and Consumption

Phase 2 · Completed · Brown University

Does Guanfacine Attenuate Stress-Induced Drinking?

Phase 2 · Completed · Yale University

Fyn Kinase Inhibitors and Alcohol Drinking

Phase 2 · Completed · Yale University

Efficacy of Gabapentin in Alcohol Dependency Treatment: a Double-blinded Randomized Placebo-controlled Trial

Phase 3 · Completed · Chulalongkorn University

Topiramate Treatment of Problem Drinkers

Phase 4 · Completed · UConn Health

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

ADH1B0.57ADH1C0.57ALDH20.55ABCA10.51MPDZ0.50FURIN0.49BARHL20.48CDH40.48PTPRT0.48GPAM0.48MTARC10.47DPP100.47

Disease biology

6 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Phospholipid-transporting ATPase ABCA1via ABCA10.51Serotransferrinvia TF0.46Potassium channel subfamily K member 3via KCNK30.44Mucin-16via MUC160.42Semaphorin-3Avia SEMA3A0.42Potassium voltage-gated channel subfamily A member 4via KCNA40.40

Reference

Authoritative identity, definition & identifiers.

Synonyms

alcohol consumption

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.