Amblyopia
Recent clinical, regulatory, research and industry developments relating to this disease.
Harnessing brain plasticity to improve binocular vision in amblyopia: An evidence-based update.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 1 clinical trial with recent milestones.
- 2 industry developments reported.
Clinical MilestonesViewHide
Industry & MarketViewHide
- 2026-08-17Comment on:Have Deprivation Amblyopia Outcomes Improved for Infants With Unilateral Cataracts?Industry · American Journal of Ophthalmology
- 2026-08-16Reply to Comment on “Have deprivation amblyopia outcomes improved for infants with unilateral cataracts?Industry · American Journal of Ophthalmology
- 2026-08-17IndustryComment on:Have Deprivation Amblyopia Outcomes Improved for Infants With Unilateral Cataracts?Industry · American Journal of Ophthalmology
- 2026-08-16IndustryReply to Comment on “Have deprivation amblyopia outcomes improved for infants with unilateral cataracts?Industry · American Journal of Ophthalmology
- 2026-03-01ClinicalPossible Beneficial Effects Of Combined Fluoxetine And Occlusion Therapy In Improving And Maintaining Vision In Amblyopia Using Optical Coherence Tomography Angiography (OCTA) And Visual Evoked Potential (VEP)Primary completion
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes4
- Amblyopia1
- Neuronal Plasticity1
- Vision, Binocular1
- Visual Acuity1
Leading journals1
- European journal of ophthalmology1
Leading researchers5
- Bex P1
- Concetta Morrone M1
- Lozama A1
- Sabel BA1
- Thompson B1
Affiliations (unnormalised)5
- Centre for Eye and Vision Science1
- Institute of Medical Psychology1
- Northeastern University1
- University of Pisa1
- University of Waterloo1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.