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NPLOC4

Gene

NPL4 homolog, ubiquitin recognition factor

HGNCHGNC:18261EnsemblENSG00000182446NCBI Gene55666
Locus: gene with protein productLocation: 17q25.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNPL4 · FLJ20657 · KIAA1499
View full nomenclature history (5)
Alias symbolsNPL4, FLJ20657, KIAA1499
Previous namesnuclear protein localization 4 homolog (S. cerevisiae), NPLOC4 ubiquitin recognition factor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Dengue
Hair color
Myopia
Cataract
Amblyopia
Refractive Errors

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers RANBP2-typeVCP-Ufd1-Npl4 complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.