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Disease

Bicuspid Aortic Valve Disease

Active therapeutic pipelineEmerging researchRising momentum
MeSHBicuspid Aortic Valve Disease
3
Publications
1
Clinical trials
3
Related conditions
2022
Latest publication
Latest activity
beta

Recent clinical, regulatory, research and industry developments relating to this disease.

2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.

Research2022-11-02Circulation

2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC).

Research2014-08-29European heart journal

2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA).

Research2013-06-24European heart journal

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

Executive briefingUpdating summary…Momentum: Low
Key developments
  • 1 clinical trial expected to report results, the earliest in Q3 2032.
Upcoming Milestones
Major developments
Upcoming trial readoutImportant
Bicuspid Aortic Valve Replacement: EvaLuatIon of transcathetEr VERsus Surgery (BELIEVERS) Trial
Results expected Q3 20322026-08-14
Clinical Milestones1View
Results expected 1
Activity timeline1

Clinical trials

1 sponsors · 1 new · 0 completed in the last 12 months (net +1)

The current development programme across all trial phases.

Clinical programme
1
All trials
1
Active
0
Late-stage
0
Completed

Research activity

3 papers

Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.

Publications over time
20132022
Most influential

2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC).

European heart journal · 2014 · 3,080 cites

2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA).

European heart journal · 2013 · 1,359 cites

2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.

Circulation · 2022 · 1,178 cites
Recent publications

2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.

Circulation · 2022 · 1,178 cites

2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC).

European heart journal · 2014 · 3,080 cites

2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA).

European heart journal · 2013 · 1,359 cites
Major themes5
  • Aorta, Abdominal1
  • Aorta, Thoracic1
  • Aortic Diseases1
  • Bicuspid Aortic Valve Disease1
  • Cardiology1
Leading journals2
  • European heart journal2
  • Circulation1
Leading researchers8
  • Sirnes PA2
  • Aboyans V1
  • Achenbach S1
  • Aliyev F1
  • Allmen RS1
  • Augoustides JG1
  • Auricchio A1
  • Badano LP1
Affiliations (unnormalised)2
  • AHA/ACC Joint Committee on Clinical Data Standards liaison.1
  • AHA/ACC Joint Committee on Clinical Practice Guidelines liaison.1

Related conditions

3 matches

Diseases frequently studied alongside this one. Number shows shared papers.

Aortic Diseases2Heart Defects, Congenital2Heart Valve Diseases2

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

Congenital heart valve defects where the AORTIC VALVE has two instead of normal three cusps. It is often associated with AORTIC REGURGITATION and AORTIC INSUFFICIENCY.

Identifiers
MeSHBicuspid Aortic Valve Disease
References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.