Carpal Tunnel Syndrome
Recent clinical, regulatory, research and industry developments relating to this disease.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 3 clinical trials expected to report results, the earliest in Q1 2027.
- Q1 2027The NOR-CACTUS Trial - A Norwegian Trial Comparing Treatment Strategies for Carpal Tunnel Syndrome
- Q4 2027Clinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol.
- Q4 2027Exparel and Education to Avoid Opioids After Carpal Tunnel Release
Clinical MilestonesViewHide
- 2026-07-09Clinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol.Results expected Q4 2027
- 2026-04-08Exparel and Education to Avoid Opioids After Carpal Tunnel ReleaseResults expected Q4 2027
- 2026-03-27The NOR-CACTUS Trial - A Norwegian Trial Comparing Treatment Strategies for Carpal Tunnel SyndromeResults expected Q1 2027
- 2026-04-01The Use of N-acetylcysteine Supplementation in Addition to Night Splinting for Treatment of Mild to Moderate Carpal Tunnel Syndrome: A Randomized, Double-blind, Placebo-controlled TrialPrimary completion
- 2026-03-30Comparison of Hydrodissection With 5% Dextrose and Perineural Corticosteroid Injection in Carpal Tunnel Syndrome: A Prospective StudyCompleted
- 2026-01-01Comparison of the Efficacy Between Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone Injection in Patients With Carpal Tunnel Syndrome: a Prospective, Randomized Double-blind Clinical Trial.Primary completion
- 2026-07-09ClinicalClinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol.Results expected Q4 2027
- 2026-04-08ClinicalExparel and Education to Avoid Opioids After Carpal Tunnel ReleaseResults expected Q4 2027
- 2026-04-01ClinicalThe Use of N-acetylcysteine Supplementation in Addition to Night Splinting for Treatment of Mild to Moderate Carpal Tunnel Syndrome: A Randomized, Double-blind, Placebo-controlled TrialPrimary completion
- 2026-03-30ClinicalComparison of Hydrodissection With 5% Dextrose and Perineural Corticosteroid Injection in Carpal Tunnel Syndrome: A Prospective StudyCompleted
- 2026-03-27ClinicalThe NOR-CACTUS Trial - A Norwegian Trial Comparing Treatment Strategies for Carpal Tunnel SyndromeResults expected Q1 2027
- 2026-01-01ClinicalComparison of the Efficacy Between Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone Injection in Patients With Carpal Tunnel Syndrome: a Prospective, Randomized Double-blind Clinical Trial.Primary completion
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes3
- Diabetes Mellitus, Type 21
- Mendelian Randomization Analysis1
- Nervous System Diseases1
Leading journals1
- Medicine1
Leading researchers6
- Bao M1
- He B1
- Wei Y1
- Wu Z1
- Xu S1
- Zhang M1
Affiliations (unnormalised)5
- Hunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations1
- School of Life Sciences1
- School of Pharmaceutical Science1
- School of Stomatology1
- The Hunan Provincial Key Laboratory of the TCM Agricultural Biogenomics1
Reference
Authoritative identity, definition & identifiers.
Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.