Chordoma
Recent clinical, regulatory, research and industry developments relating to this disease.
Chordoma: Genetics and Contemporary Management.
What's happening now
An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.
- 2 clinical trials expected to report results, the earliest in Q2 2027.
Clinical MilestonesViewHide
- 2026-04-28A Phase 1b/2 Study of ERAS-601 SHP2 Inhibitor as a Monotherapy in Patients With Advanced and Progressing ChordomaResults expected Q2 2027
- 2026-04-13A Phase II Clinical Study to Evaluate the Efficacy and Safety of BL-B01D1 for Injection in Patients With Locally Advanced or Metastatic ChordomaResults expected Q2 2027
- 2026-09-01A Phase II Trial of Cetuximab for Patients With Advanced or Metastatic ChordomaPrimary completion
- 2026-05-01DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare TumorsPrimary completion
- 2026-09-01ClinicalA Phase II Trial of Cetuximab for Patients With Advanced or Metastatic ChordomaPrimary completion
- 2026-05-01ClinicalDART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare TumorsPrimary completion
- 2026-04-28ClinicalA Phase 1b/2 Study of ERAS-601 SHP2 Inhibitor as a Monotherapy in Patients With Advanced and Progressing ChordomaResults expected Q2 2027
- 2026-04-13ClinicalA Phase II Clinical Study to Evaluate the Efficacy and Safety of BL-B01D1 for Injection in Patients With Locally Advanced or Metastatic ChordomaResults expected Q2 2027
Clinical trials
The current development programme across all trial phases.
Research activity
Key research shaping understanding of this disease, combining the latest publications with the most influential evidence.
Major themes1
- Chordoma1
Leading journals1
- International journal of molecular sciences1
Leading researchers3
- Desai R1
- Dunn IF1
- Pelargos PE1
Affiliations (unnormalised)1
- University of Oklahoma1
Associated genes
Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.
Disease biology
Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.
Reference
Authoritative identity, definition & identifiers.
A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)
- Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
- Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
- Research activity — Europe PMC (EMBL-EBI) + OpenAlex-derived paper links
- Related entities are derived from literature co-mention (studied together) — associative, not causal.